双歧杆菌
益生菌
短双歧杆菌
粪便
生物
放线菌科
微生物学
人类粪便
选择(遗传算法)
细菌
拉伤
食品科学
发酵
乳酸菌
遗传学
解剖
人工智能
计算机科学
作者
Maria Carmen Collado,Yolanda Sanz
标识
DOI:10.1016/j.mimet.2006.01.007
摘要
A method for direct selection of acid-resistant Bifidobacterium strains was developed by prolonged exposure of human feces to homologous lethal stress conditions. The recovered strains were intrinsically resistant to acidic gastric conditions (pH 2.0) and also showed good tolerance to high concentrations of bile salts and NaCl. Bifidobacterium breve and Bifidobacterium adolescentis were, respectively, the infant- and adult-type bifidobacterial species showing the highest ability to develop an acid-tolerant phenotype. Therefore, this procedure could be applicable to the direct selection of Bifidobacterium strains with improved stability in adverse environments and, probably, contribute to expand the spectra of probiotic species of human origin currently marketed.
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