Crosstalk Between Cell–Cell and Cell–Matrix Adhesion

This chapter contains sections titled: Introduction Coordinate Regulation of Cell–Cell and Cell–Matrix Adhesion Crosstalk Between Integrins and Cadherins Mechanisms of Integrin–Cadherin Crosstalk Extracellular Proteolysis Cross-Regulation of Gene Expression Changes in Intracellular Force Generation Integrin–Cadherin Associations at Sites of Cell Adhesion Intracellular Signal Transduction Pathways FAK: An Integrin Effector that Signals to Cadherins Fer: A Tyrosine Kinase that Translocates between Cadherins and Integrins Rap1: A Central Regulator of Integrin–Cadherin Crosstalk Pathways? The Epidermis as a Model for Investigating Cadherin–Integrin Crosstalk Future Prospects Acknowledgments References