Study on Preventive Intervention of Peri-knee Ecchymosis After Total Knee Replacement

Objective: To investigate the effectiveness, controllability and safety of fresh plasma infusion in preventing ecchymosis after total knee arthroplasty (TKA). Methods: Patients with osteoarthritis of the knee who received the initial TKA were assigned to study group, control group, and blank control group according to APTT and PT results on the first day postoperatively. Patients in the study group received 400ml fresh frozen plasma infusion on the first day after TKA, and patients in the control group and blank control group received conventional postoperative treatment. The incidence of ecchymosis, the circumference of the affected limb and visual analog scale (VAS) were compared and analyzed in the three groups. Results: 20 patients were included into each group, respectively. After the infusion of fresh frozen plasma, the number of peri-knee ecchymosis in the study group was significantly less than that in the control group on the 7th and 14th days after the operation (P<0.05). On the 14th day after operation, the circumference of the affected limb in the study group was significantly lower than that in the control group (P<0.05), the circumference of the affected limb in the control group was higher than that in the blank control group, and the circumference of the affected limb in the study group was similar to that in the blank control group (P>0.05). On the 7th and 14th day after surgery, the pain degree of the three groups was relieved, and the VAS score of the study group and the blank control group showed no statistically significant difference (P>0.05), while the VAS score of the study group was lower than that of the control group, the difference was statistically significant (P<0.05). Conclusion: For patients with abnormal coagulation function after TKA, timely postoperative infusion of fresh frozen plasma can reduce the incidence of postoperative ecchymosis and relieve pain, which has certain clinical reference significance.