Osteoporosis is a skeletal disorder characterized by low bone mass, increased bone fragility, and susceptibility to fracture. It is of mainly into two types. Glucocorticoid induced osteoporosis occurs mainly due to the usage of glucocorticoids for prolonged periods. Glucocorticoid induced osteoporosis ranks third in importance as a risk factor for osteoporosis. It is mainly diagnosed by blood and urine estimations. The first choice of drugs for the treatment of glucocorticoid induced osteoporosis is bisphosphonates.