Objective: To assess the level of caregiver burden among lung cancer caregivers and to explore its indicators.And provide evidence and new ideas to improve the mental health of lung cancer caregivers.Methods: A cross-sectional study was conducted and data was collected by face-to-face interview.Zarit caregiver burden interview(ZBI) was used to access the level of caregiver burden.Results: The ZBI score of lung cancer caregiver was 29.8±16.8,nearly 74.29% of caregivers experienced the low level of caregiver burden.The extent of the impact of caregiving on the family caregivers' transportation and health were the risk factors,while sleeping hours and sense of coherence were the protective factors.Conclusion: Interventizons should be emphasized on increasing sleeping hours and establishing compensation mechanism for nursing care and enhancing the levels of sense of coherence-coping ability,so as to cope with caregiver burden.