Objective:To investigate the effect of the two wild lymph node dissection treatment to lower esophageal cancer.Methods:Two wild patients with lymph node dissection(n=35) used single incision,compared with 27 cases who used two incisions from January 2009 to July 2011.The operative time,number of lymph node dissection,post-operative recovery time and the cancer residual differences were analyzed.Results:In the single-incision group,operation time was shorter,the number of lymph node dissection was fewer,those were significantly different compared with two incisions group(P0.05).The recovery time and cancer residual,and hospital stay were not significant different between the two groups(P0.05).Conclusion:The use of single incision and two incision two wild lymph node dissection treatment to lower esophageal cancer also have good therapeutic effect,and doctor can choose according to the patient's actual situation choice.