液体活检
医学
活检
头颈部癌
微小残留病
循环肿瘤细胞
癌症
疾病
疾病监测
头颈部
个性化医疗
肿瘤科
病理
内科学
放射科
外科
生物信息学
转移
生物
骨髓
作者
Shrikant Balasaheb Mali
出处
期刊:Oral Oncology
[Elsevier BV]
日期:2023-07-01
卷期号:144: 106481-106481
被引量:3
标识
DOI:10.1016/j.oraloncology.2023.106481
摘要
Liquid biopsy has become a significant tool in personalized medicine, enabling real-time monitoring of cancer evolution and patient follow-up. This minimally invasive procedure analyzes circulating tumor cells (CTCs) and circulating tumor-derived materials, such as ctDNA, miRNAs, and EVs. CTC analysis significantly impacts prognosis, detection of minimal residual disease (MRD), treatment selection, and monitoring of cancer patients. Liquid biopsy is an attractive option for mouth cancer detection and treatment progress monitoring in many countries. It is not invasive and requires no surgical expertise, making it an attractive option for mouth cancer detection. Liquid biopsy is a diagnostic repeatable test that can profile cancer genomes in real-time with minimal invasiveness and tailor oncological decision-making. It analyzes different blood-circulating biomarkers, with ctDNA being the preferred one. While tissue biopsy remains the gold standard for molecular evaluation of solid tumors, liquid biopsy is a complementary tool in various clinical settings, including treatment selection, monitoring response, cancer clonal evolution, prognostic evaluation, early disease detection, and minimal residual disease (MRD).
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