去卵巢大鼠
胶囊
化学
NF-κB
TLR2型
细胞生物学
内分泌学
内科学
信号转导
生物
医学
生物化学
植物
TLR4型
激素
作者
Lingfeng Zeng,Jinlong Zhao,Zhuoxu Gu,Di Zhao,Guanghui Zhou,Junzheng Yang,Jianke Pan,Weiyi Yang,Jun Liu,Guihong Liang
出处
期刊:Phytomedicine
[Elsevier]
日期:2025-04-01
卷期号:141: 156705-156705
标识
DOI:10.1016/j.phymed.2025.156705
摘要
This study highlighted that GSA capsule attenuated inflammation and augmented osteogenic differentiation of BMSCs by targeting the TLR2/NF-κB pathway. These molecular mechanisms contributed to enhanced BMD and bone microarchitecture in OVX rats, suggesting the therapeutic potential of GSA capsule in OP management.
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