医学
支气管扩张
铜绿假单胞菌
PSL公司
单克隆抗体
免疫学
微生物学
抗体
细菌
内科学
肺
几何学
数学
遗传学
生物
作者
Merete Long,Amy Gilmour,Margaret Kehl,David E. Tabor,Ashley Keller,Paul Warrener,Vancheswaran Gopalakrishnan,Sanna Rosengren,Megan Crichton,Eve Mcintosh,Yan Hui Giam,Holly R. Keir,Wayne Brailsford,Rod Hughes,Maria G. Belvisi,Bret R. Sellman,Antonio DiGiandomenico,James D. Chalmers
标识
DOI：10.1164/rccm.202308-1403oc
摘要
infection is associated with worse outcomes in bronchiectasis. Impaired neutrophil antimicrobial responses contribute to bacterial persistence. Gremubamab is a bivalent, bispecific monoclonal antibody targeting Psl exopolysaccharide and the type 3 secretion system component PcrV.
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