巨噬细胞极化
巨噬细胞
造血
祖细胞
骨髓
刺激
体外
免疫学
细胞生物学
化学
干细胞
生物
神经科学
生物化学
作者
Wei Ying,Patali S. Cheruku,Fuller W. Bazer,Stephen Safe,Beiyan Zhou
摘要
The article describes a readily easy adaptive in vitro model to investigate macrophage polarization. In the presence of GM-CSF/M-CSF, hematopoietic stem/progenitor cells from the bone marrow are directed into monocytic differentiation, followed by M1 or M2 stimulation. The activation status can be tracked by changes in cell surface antigens, gene expression and cell signaling pathways.
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