Pimecrolimus for Steroid Rosacea

Some patients with rosacea, perioral dermatitis, or other conditions develop a rosacea-like eruption after treatment with topical corticosteroids, particularly fluorinated ones. Called steroid-induced rosacea or steroid rosacea, it appears as an eruption of papules and pustules on ruddy skin near the mouth. The eruption responds to resumption of topical steroids but usually flares again when treatment is stopped. Lee and colleagues studied the effectiveness of pimecrolimus, a nonsteroidal anti-inflammatory agent, for steroid-induced rosacea in 18 subjects who had pruritic facial papules, …