Objective To observe the clinical curative effect of angina treatment with Kaishi.Methods 38 cases of coronary heart disease were treated with 10 μg kaishi intravenously.Results There were 86.8% excellent,7.9% good and 5.3% no-effect in 38 cases.The total effective rate was 94.7%.Conclusion Kaishi might be effective drug to treat coronary heart disease and angina.