Mankind went through the industrial economy and entered in the age of economy,this caused a series of changes,such as economic structure,culture,value,etc.Marx's labor faces the new challenge too.The views,such as labor-knowledge axioiogy,knowledge axiology have appeared.This text proceeds with the relation between labor and axiology,analyzes several prevailing relation theories represented by denying theory,replacement theoryand theory. On the basis,the text points out that the value theory follows the development rule fromlabour axiology to labor-knowledge axiology,and then will reach the knowledge axiology.