To manage the medical waste disposal in hospital in a standardized way. The management on medical waste disposal in Harbor Hospital was evaluated. To accord with the Regulations for Medical Waste Management, the managerial system and principles were improved. Staff training was conducted, medical staff's consciousness was aroused and the medical waste was disposed in classified way. [Conclusion] The medical waste disposal system is effective and instructive for clinical work, which can effectively reduce the hazard of medical waste on the environment and human people's health