三体
非整倍体
医学
产科
胎儿游离DNA
大规模并行测序
颈部透明度测量
产前诊断
置信区间
唐氏综合症
基因检测
怀孕
胎儿
妇科
染色体
遗传学
内科学
生物
DNA测序
DNA
基因
精神科
作者
Diana W. Bianchi,Richard Parker,Jeffrey Wentworth,Rajeevi Madankumar,Craig Saffer,A. Das,Joseph A. Craig,Darya Chudova,Patricia Devers,Keith Jones,Kelly Oliver,Richard P. Rava,Amy J. Sehnert
标识
DOI:10.1056/nejmoa1311037
摘要
In a general obstetrical population, prenatal testing with the use of cfDNA had significantly lower false positive rates and higher positive predictive values for detection of trisomies 21 and 18 than standard screening. (Funded by Illumina; ClinicalTrials.gov number, NCT01663350.).
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