Bortezomib:a proteasome inhibitor in the treatment of multiple myeloma

Proteasome inhibitor bortezomib has a very powerful anti-myeloma effect on both preclinical and clinical trails.it has been widely used in the treatment of newly diagnosed,refractory and relapse multiple myeloma.Its side effects were well tolerant and manageable. Key words: Multiple myeloma; Protease inhibitor