Impact of Postsynthetic Modification on the Covalent Organic Framework (COF) Structures

Covalent organic frameworks (COFs) have emerged as a versatile class of materials owing to their well-defined crystalline structures and inherent porosity. In the realm of COFs, their appeal lies in their customizable nature, which can be further enhanced by incorporating diverse functionalities. Postsynthetic modifications (PSMs) emerge as a potent strategy, facilitating the introduction of desired functionalities postsynthesis. A significant challenge in PSM pertains to preserving the crystallinity and porosity of the COFs. In this study, we aim to investigate the intricate interplay between PSM strategies and the resulting crystalline and porous structures of the COFs. The investigation delves into the diverse methodologies employed in PSMs, to elucidate their distinct influences on the crystallinity and porosity of the COFs. Through a comprehensive analysis of recent advancements and case studies, the study highlights the intricate relationships among PSM parameters, including reaction conditions, precursor selection, and functional groups, and their impact on the structural features of COFs. By understanding how PSM strategies can fine-tune the crystalline and porous characteristics of COFs, researchers can harness this knowledge to design COFs with tailored properties for specific applications, contributing to the advancement of functional materials in diverse fields. This work not only deepens our understanding of COFs but also provides valuable insights into the broader realm of PSM strategies for other solid materials.