认知
老年学
认知功能衰退
队列
神经心理学
置信区间
队列研究
医学
临床心理学
人口学
痴呆
精神科
疾病
内科学
社会学
作者
Guirong Cheng,Dan Liú,Lin‐Ya Huang,Gang‐Bin Han,Feifei Hu,Zhao‐Xia Wu,Xiao‐Ming He,Yu‐Wei Huang,Ya‐Fu Yu,Li‐Yan Xu,Jinquan Li,Yu‐Shan Chen,Zhen Wei,Qiong Wu,Yufei Mei,Xing‐Xing Chen,Yangming Ou,Jing‐Jing Zhang,Mengliu Yang,Pengfei Lian,Wei Tan,Xinyan Xie,Yan Zeng
摘要
The prevalence and risk factors for subjective cognitive decline (SCD) and its correlation with objective cognition decline (OCD) among community-dwelling older adults is inconsistent.Older adults underwent neuropsychological and clinical evaluations to reach a consensus on diagnoses.This study included 7486 adults without mild cognitive impairment and dementia (mean age: 71.35 years [standard deviation = 5.40]). The sex-, age-, and residence-adjusted SCD prevalence was 58.33% overall (95% confidence interval: 58.29% to 58.37%), with higher rates of 61.25% and 59.87% in rural and female subgroups, respectively. SCD global and OCD language, SCD memory and OCD global, SCD and OCD memory, and SCD and OCD language were negatively correlated in fully adjusted models. Seven health and lifestyle factors were associated with an increased risk for SCD.SCD affected 58.33% of older adults and may indicate concurrent OCD, which should prompt the initiation of preventative intervention for dementia.SCD affects 58.33% of older adults in China. SCD may indicate concurrent objective cognitive decline. Difficulty finding words and memory impairments may indicate a risk for AD. The presence of SCD may prompt preventative treatment initiation of MCI or dementia. Social network factors may be initial targets for the early prevention of SCD.
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