大肠杆菌
微生物学
生物
免疫
益生菌
免疫系统
拉伤
先天免疫系统
细菌
肠杆菌科
免疫学
基因
遗传学
解剖
作者
I Trebichavský,Igor Šplı́chal,V. Rada,Alla Šplı́chalová
出处
期刊:Nutrition Reviews
[Oxford University Press]
日期:2010-07-20
卷期号:68 (8): 459-464
被引量:68
标识
DOI:10.1111/j.1753-4887.2010.00305.x
摘要
The beneficial effect of probiotic Escherichia coli strain Nissle 1917 (EcN) suggests the gut epithelium plays a basic role in immune interactions with bacteria. Contrary to other commensal strains of Escherichia coli, EcN profoundly modulates the gut barrier to elevate its resistance to microbial pathogens. The present review documents the properties of EcN that have led to the protection of gnotobiotic pigs against lethal enteric infections. This effect could be important in light of the growing number of acquired deficiencies that paralyze gut immunity in humans.
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