At present, five distinct human hepatotropic viruses have been characterized (1). These viruses differ significantly from each other in their genomic organization and are classified into distinct viral families. They are transmitted either parenterally or enterically. The parenterally transmitted viruses are hepatitis B virus (HBV), hepatitis C virus (HCV), and hepatitis D (delta) virus (HDV). The enterically transmitted viruses are hepatitis A virus (HAV) and hepatitis E virus (HEV).