Construction of pyrazolo[5,1-a]isoindol-8(3aH)-one derivatives via phosphine-catalyzed cyclization of electron-deficient alkynes and N-amino substituted phthalimide

A novel method for the synthesis of diversely functionalized pyrazolo[5,1- a ]isoindol-8(3 aH )-ones is developed via phosphine-catalyzed reaction of electron-deficient alkynes and N -amino substituted phthalimide.