Clinical study of therapeutic effect of chinese herbs decoction and Tuian Yun-jinyi treatment combined with endoscopic therapy in acute obstructive cholangitis

Objective:To observe the therapeutic effect of chinese herbs decoction and Tuian Yunjinyi(TAYJY) combined with endoscopic therapy in the treatment of patients suffered from acute obstructive cholangitis(AOC).Methods:Sixty nine patients in AOC underwent EST were devided randomly into 3 groups:23 of them treated by Chinese herbs decoction with endoscopic therapy(Chinese herbs decoction combined therapy group),and other 23 of them treated by Chinese herbs decoction and TAYSY with endoscopic therapy(TAYJY combined therapy group),the other 23 patients were treated with endoscopic therapy(control group alone).Results:The results showed that the level of serum bilirubin,ALT,endotoxin was obviously reduced in the combined therapy group compared with control group(P0.01);significant increases of superoxide dismutase(SOD) activity and level were found in the combined therapy group(P0.01).Conclusion:Endoscopic therapy combined with Chinese herbs decoction and TAYSY have better effect for treation acute obstructive cholangitis.