垂体机能减退
医学
呼吸衰竭
淋巴瘤
呼吸系统
尸检
感染性休克
垂体前叶
病理
内科学
心脏病学
败血症
激素
作者
Tatsuaki Kosaka,Yuki Honda,Yoichiro Homma,Masao Nakata
出处
期刊:Case Reports
[BMJ]
日期:2022-05-01
卷期号:15 (5): e247880-e247880
标识
DOI:10.1136/bcr-2021-247880
摘要
We report a rare case of intravascular large B-cell lymphoma (IVLBCL) with hypopituitarism and respiratory failure. A man in his 80s presented with hypotension and respiratory failure but was unsuccessfully treated for septic shock. Biological investigations were performed, and he was diagnosed with hypopituitarism due to insufficient secretion of anterior pituitary hormone. Although his condition temporarily improved following hormone replacement therapy, he eventually died of progressive respiratory failure. The lymphoma was only discovered during the autopsy, where it was observed to have spread to the pituitary gland and lung capillaries. Therefore, we concluded that the lymphoma had caused respiratory failure and hypopituitarism. The patient was thus diagnosed with IVLBCL posthumously. In conclusion, IVLBCL can cause hypopituitarism and respiratory failure due to pituitary and pulmonary capillary invasion by lymphoma cells.
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