Electrochemical Dehydrogenative Coupling Between P(O)─H Compounds and Oximes (─NO─H)

Abstract In this study, we demonstrate an electrochemical dehydrogenative coupling strategy for N─O─P bond formation. Various kinds of ketone oximes, phosphine oxides, and phosphite esters were demonstrated to be efficient substrates, generating the desired phosphorylated oximes in the presence of ammonium iodide as an electrolyte at room temperature. A reliable mechanism is proposed after control and cyclic voltammetry experiments.