Studies on Sinomenine

A short survey of sinomenine investigation is given in the theoretical part, principally on the transformation of sinomenine derivatives, hitherto almost unnoticed in morphine derivatives. In experimental, the preparation of (+)-codeinone from sinomenine, reduction of l-bromocodeinone and similar compounds with SnCl2+HCl, and the use of NaBH4 on the reduction of the ketonic group in sinomenine derivatives are described.