萧条(经济学)
帕金森病
疾病
抑郁症状
运动症状
精神科
医学
生活质量(医疗保健)
心理学
神经学
临床心理学
心理治疗师
内科学
焦虑
宏观经济学
经济
作者
M.H.M. Timmer,M.H.C.T. van Beek,B.R. Bloem,Rianne A.J. Esselink
出处
期刊:Practical Neurology
[BMJ]
日期:2017-07-24
卷期号:17 (5): 359-368
被引量:63
标识
DOI:10.1136/practneurol-2017-001650
摘要
Depression is a frequent non-motor symptom of Parkinson's disease. Its prevalence varies widely across studies (between 2.7% and 90%); around 35% have clinically significant depressive symptoms. Although depression can have an immense impact on the quality of life of affected patients and their caregivers, depressive symptoms in Parkinson's disease frequently remain unrecognised and, as a result, remain untreated. Here we overview the diagnostic challenges and pitfalls, including the factors contributing to the underdiagnosis of depression. We also discuss current ideas on the underlying pathophysiology. Finally, we offer a treatment approach based on currently available evidence.
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