2型糖尿病
多酚
医学
糖尿病
糖尿病管理
饮食管理
药理学
重症监护医学
内科学
内分泌学
化学
生物化学
抗氧化剂
作者
Sisir Kumar Barik,Srabasti Sengupta,Rakesh Arya,Surendra Kumar,Jong-Joo Kim,Reetika Chaurasia
标识
DOI:10.1016/j.advnut.2024.100346
摘要
Poor dietary intake or unhealthy lifestyle contributes to various health disorders, including postprandial hyperglycemia, leading to type 2 diabetes mellitus (T2DM). Reduction of postprandial glucose concentrations through diet is a key strategy for preventing and managing T2DM. Thus, it is essential to understand how dietary components affect glycemic regulation. Dietary polyphenols (DPs), such as anthocyanins and other phenolics found in various fruits and vegetables, are often recommended for their potential health benefits, although their systemic effectiveness is subject to ongoing debate. Therefore, this review assesses the current and historical evidence of DPs bioactivities, which regulate crucial metabolic markers to lower postprandial hyperglycemia. Significant bioactivities such as modulation of glucose transporters, activation of AMP kinase, and regulation of incretins are discussed, along with prospects for diet-induced therapeutics to prevent the onset of T2DM.
科研通智能强力驱动
Strongly Powered by AbleSci AI