A Biomimetic Electrocatalytic System for the Atom-Economical Chemoselective Synthesis of Secondary Amines

A facile one-pot oxidation-imine formation-reduction route to secondary amines can be achieved electrolytically from primary amines. This atom-economical 1(ox)-mediated sequence, leaving ammonia as the sole byproduct, allows the rapid chemoselective synthesis of secondary amines, at both ambient temperature and pressure.