The stress response to intraoperative pneumoperitoneum and positioning in gynecologic patient over laparoscopy

Objective To investigate the underlying risk of anesthesia in laparoscopy by observing the hemody-namic and stress response during intraoperative pneumoperitoneum and positioning. Methods 20 patients, A-SAⅠ-Ⅱ, underwent laparoscopic ovarian cystectomy. Hemodynamics, end-tidal CO2 and stress hormones were measured at before operation,pre-pneumoperitoneum,post-pneumoperitoneum,post-positioning,resumed position and released pneumoperitoneum. Results Hemodynamics changed significantly after pneumoperitoneum and positioning(P0.05). The end-tidal CO2 did not change obviously(P0. 05). Adrenaline,noradrenaline and cortisol increased significantly when pneumoperitoneum released and resumed the position( P 0.05) ,however, adrenaline and noradrenaline did not increase significantly after pneumoperitoneum which compared with preop-erative values. Conclusion Pneumoperitoneum and positioning can cause hemodynamics and stress hormones increased over laparoscopy.