Objective To evaluate the clinical characteristics and occurrence rules of silent myocardial ischemia(SMI) in patients with coronary artery disease.Methods Sixty-eight patients with coronary artery disease were investigated by 24-hour ambulatory electrocardiogram,to observe myocardial ischemic threshold and variability of cardial ischemic threshold.Results Myocardial ischemia was found to occur 403 times,and symptomatic ischemia was 46 times,the incidence rate of the former was higher than the latter.Conclusion SMI is the most common manifestation in patients with coronary artery disease.There are different kinds of mechanism in myocardial ischemia.It is necessary for us to use different methods in treatment.