小RNA
医学
糖尿病
病态的
慢性伤口
伤口愈合
生物信息学
重症监护医学
外科
内科学
内分泌学
生物
基因
生物化学
作者
Yi-Xuan Fang,Lihong Chen,Yan Li,Xingwu Ran
出处
期刊:PubMed
日期:2022-11-01
卷期号:53 (6): 949-952
摘要
Diabetic chronic wound is one of the most serious complications of diabetes, imposing enormous socioeconomic burdens on diabetic patients, their families, and society due to its refractory nature. MicroRNAs (miRNAs) have emerged as important regulators of various physiological and pathological processes. Abnormalities arise in the regulatory functions of miRNAs in chronic diabetic wounds. Therefore, the modification of miRNAs expression in diabetic wounds is an important channel for the improvement of wound healing. The clinical translation of miRNA-based therapy may become a prospective direction of diabetic wound healing. However, miRNA-based therapy is still in its early stage of development, and actual translation into clinical application will take a long time. Herein, we summarized the latest research findings on miRNAs in diabetic chronic wounds healing.
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