Resurgence of pediatric Mycoplasma pneumoniae infections in Southeast Texas, Nov 2023-June 2024

We conducted a retrospective review of children tested for Mycoplasma pneumoniae from January 1, 2020-June 30, 2024. M. pneumoniae PCR positivity increased starting in November 2023, peaking at 18.3% in June 2024. During the resurgence, children with laboratory-confirmed infection often had severe respiratory disease or extrapulmonary manifestations.