Formulation and In-Vitro Evaluation of Tenofovir Disoproxil Fumarate Immediate Release Tablets.

Tablets are tamper proof solid unit dosage forms containing medicament or mixture of medicaments and excipients compressed or moulded into solid cylindrical shape having either flat or convex surfaces. stability study it was found that there was no significant change in hardness, drug content, disintegration time and In-Vitro dissolution of optimized formulation F6. It may be concluded that the Immediate release tablets of Tenofovir disoproxil fumarate was feasible and may be manufactured with reproducible characteristics with the aid of Croscarmellose sodium as disintegrant. From the above all trials we conclude that formulation F6 obeys all the results within the Standard limits as that of innovator product. However it needs further in depth In Vivo release studies on suitable animal models with statistical clinical data for a dependable and successful pharmaceutical marketing formulation