Automation and Robotics with the Roche Ventana BenchMark ULTRA

Roche’s answer to current immunohistochemistry automation is the Ventana BenchMark ULTRA. An evaluation of the machine’s design, operation and maintenance is provided from a user’s viewpoint. Technologies which differentiate Ventana from other manufacturers are discussed in detail. The liquid coverslip, hapten-based detection system and random access points are examples of these differences when compared to traditional coverplate and polymer technology as used by other vendors. A commentary about proprietary reagents and staining protocols are offered along with advice on achieving workflow efficiencies. Discovering quality control measures of the instrument is another topic covered. Ultimately, it is hoped the reader understands the intricacies of this platform and the advantages and disadvantages of such a system, and gains a sense of the technology behind the BenchMark ULTRA.