Isolation and Identification of Chemical Constituents from Peronia verruculata

OBJECTIVE:To isolate and identify chemical components of Peronia verruculata.METHODS:Silica gel column chromatography was used to isolate components from petroleum ether and ethyl acetate fractions of methanol extract from P.verruculata.Their structures of isolated components were elucidated by spectrum data and physical and chemical properties.RESULTS:5 compounds were obtained and elucidated as 2,2′-oxybis(1,4-di-tert-butylbenzene)(1),cholesterol(2),α-monpalmitin(3),uracil(4),thymine(5).Among them,compound 1 was reported as a natural product for the first time,and all of these compounds were isolated from P.verruculata for the first time.CONCLUSIONS:These data provides a reference for further study of Onchidium hongkongensis as animal medicines.