Convenient Synthesis of Symmetrical Functionalized Biaryls from Aryl Halides Catalyzed by Palladium on Carbon

A convenient and efficient synthesis of symmetrical functionalized biaryls from aryl halides catalyzed by 10% Pd/C (2.0mol%) in the presence of Na3PO4.12H2O and MeOH has been developed. Aryl bromides bearing electron withdrawing and electron donating groups provided homocoupling products in excellent yields. Aryl chlorides and aryl iodides provided homocoupling products in good yields. The substrates with easily reducible functional groups were also effective. Keywords: Homocoupling reaction, Pd/C, symmetrical biaryls, dimerization of aryl halides, polymers, bioactive, phosphine, palladacycles, electron