Billroth II is one of the surgical procedures used to reconstruct the upper gastrointestinal tract in dogs and cats. It is indicated when the gastrectomy is removing the pylorus, the pyloric antrum, and part of the body of the stomach. Billroth II is indicated when the resection does not allow a gastro-duodenostomy because of tension. It is recommended to remove the entire pyloric antrum during a Billroth II surgery to minimize gastrin production and acid secretion. This chapter discusses the techniques involved in Billroth II. It focuses on gastrectomy, dissection of the duodenum, gastrojejunostomy, cholecystoduodenostomy, and feeding tube. The chapter presents useful tips and tricks for a successful surgery and potential complications and post-operative care. Information on dumping syndrome, afferent loop syndrome, and gastritis and esophagitis is also provided.