Risk of perforation during endoscopic resection of esophageal lesions in patients with systemic sclerosis

It is not known whether any specific patient runs a high risk of esophageal perforation during esophageal endoscopic resection (ER). We report a case of esophageal perforation that occurred during endoscopic submucosal dissection (ESD) in a patient with systemic sclerosis (SSc) who had thin esophageal muscular layers that might have caused esophageal perforation.