To investigate the technology of extracting carotenoid from freeze drying yolk by microwave extraction,the effects of four factors,including solid-liquid ratio,microwave power,microwave temperature and microwave extraction time,on the yield of carotenoid were analyzed and compared.The optimal technological conditions were obtained using orthogonally rotational combination design.The results show that the order of factors affecting the yield of carotenoid is as follows:solid-liquid ratio,microwave time,microwave power,microwave temperature;the optimal technological conditions are:solid-liquid ratio of 23mL/g,microwave power of 600 W,microwave temperature of43℃,microwave time of 18min;under such technological conditions the yield of carotenoid is 23.99mg/(100g).