Review of clinical and pathological characteristics in 68 children with henoch-schsnlein purpura nephritics

Objective To study the relationship between the clinical and pathological characteristics in children patients with Henoch-SchSnlein purpura nephritics(HSPN).Methods We retrospectively reviewed the information of Clinical and pathological of 68 children with HSPN from January to July in 2009.Results A majority of patients exhibited hematuria,proteinunia,isolated hematuria and nephrotic syndrome while a minority showed the rapidly progressive glomerulonephritis.The pathological performs were mesangical proliferation,glomerulosclerosis and crescent formation.Most of pathological classifications were gradeⅡ or Ⅲ.Conclusions Grade Ⅱand Ⅲ of pathological classification have been seen in the majority of HPSN patients,and the clinical manifestations were closely associated with pathological classification.