中缝背核
5-羟色胺能
NMDA受体
加巴能
神经科学
抗抑郁药
萧条(经济学)
核心
心理学
生物
医学
受体
血清素
内科学
抑制性突触后电位
海马体
经济
宏观经济学
作者
Kerun Cao,Jie Zhong,Shanshan Wang,Yafei Shi,Shasha Bai,Jinlan Zhao,Liu Yang,Qi Liang,Di Deng,Rong Zhang
标识
DOI:10.1016/j.jep.2024.118040
摘要
• SiNiSan exerts therapeutic effects on adolescent depression caused by stress in early life and adolescence. • SiNiSan downregulates N-methyl-D-aspartic acid (NMDA) receptor expression and regulates serotonergic/GABAergic neuron activity in the dorsal raphe nucleus region of the adolescent depression models. • SiNiSan regulates neuronal activity by downregulating NMDA receptors in the dorsal raphe nucleus of adolescent depression models.
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