梅克尔细胞癌
默克尔细胞
免疫疗法
癌症研究
医学
癌
髓样
梅克尔多元癌细胞病毒
免疫学
病理
免疫系统
作者
Ann W. Silk,Diwakar Davar
标识
DOI:10.1158/1078-0432.ccr-23-3320
摘要
A recent report sheds light on the tumor-associated macrophages (TAM) in Merkel cell carcinoma (MCC), and the association of S100A8-expressing TAMs with resistance to anti-PD-(L)1 inhibitors. These data improve our understanding about why some tumors with brisk tumor-infiltrating lymphocytes do not respond to immunotherapy and provide a compelling rationale to target myeloid checkpoints in MCC. See related article by Tabachnick-Cherny et al., p. xxxx.
科研通智能强力驱动
Strongly Powered by AbleSci AI