Base-promoted transition-metal-free synthesis of quinazolinones with antioxidant activity

in the DPPH radical scavenging assay. Density functional theory (DFT) calculations were also conducted to provide a mechanistic understanding about the transformation. Thus, this dual-focused work not only provides an effective synthetic pathway to quinazolinones but also identifies lead compounds with noteworthy antioxidant properties for further biological investigation. These results pave the way for manufacturing innovations in the near future.