Terpenoids from Salvia trijuga

Nine new germacrane sesquiterpenes, trijugins A−I (1−9), a new lupane triterpenoid, 3α-O-acetyl-20(29)-lupen-2α-ol (10), and 24 known terpenoids were isolated from Salvia trijuga. The structure of compound 1 was confirmed by single-crystal X-ray diffraction. Compounds 1−10 and 32 were evaluated for their cytotoxicity against five human tumor cell lines. Compounds 9 and 32 exhibited moderate toxicity effects against several cell lines.