Field‐Driven Biofunctionalization of Polymer Fiber Surfaces during Electrospinning

Surface-biofunctionalized synthetic polymer fibers composed of a fiber-forming host polymer and an oligopeptide conjugate are prepared by electrospinning. The conjugate consists of a polypeptide segment and a polymer block that is compatible with the host polymer. Because the more polarizable peptide segment migrates to the surface during electrospinning, peptide surface enrichment (see figure and inside cover) is achieved in a single step without further treatment.