Hemodynamic alterations response to Chinese acupuncture therapy monitored by a custom near‐infrared spectroscopy probe with an open hole

Abstract Traditional acupuncture, a popular traditional Chinese medicine (TCM) technique, has demonstrated potential in relieving various ailments' symptoms. However, its black‐box feedback loop model has limited proper evaluation and use by unskilled practitioners. This study aimed to analyze hemodynamic signals around acupoints during acupuncture to identify significant parameter changes. We designed hollow near‐infrared spectroscopy (NIRS) probes for real‐time measurements during acupuncture at acupoints, monitoring oxy‐hemoglobin (HbO), deoxy‐hemoglobin (Hb), and blood volume (HbT) changes. Acupuncture was performed on the “Xuehai” acupoint in 17 healthy subjects, with NIRS measuring hemodynamic alterations. Results showed significant and consistent increases in Hb and HbT around the acupoint, returning to baseline values after needle removal. One case of fainting revealed a significant Hb increase and HbO decrease. Acupuncture may induce tissue vasodilation and enhance oxygen consumption. This research provides a potential explanation for acupuncture's mechanism and emphasizes NIRS's potential in TCM.