Zeta电位
纳米颗粒
胶体金
分散性
蛹虫草
材料科学
纳米技术
傅里叶变换红外光谱
粒径
核化学
化学工程
化学
冬虫夏草
高分子化学
物理化学
食品科学
工程类
作者
Girish Gawas,Muniappan Ayyanar,Nilambari Gurav,Dinesh Hase,Vaishali D. Murade,Sameer J. Nadaf,Mohd Shahnawaz Khan,Rupesh V. Chikhale,Mohan G. Kalaskar,Shailendra Gurav
摘要
The promising therapeutic implications of nanoparticles have spurred their development for biomedical applications. An eco-friendly methodology synthesizes gold nanoparticles using Cordyceps militaris, an edible mushroom (Cord-Au-NPs), using a quality-by-design approach (central composite design). UV-visible spectroscopy analysis revealed an absorption peak at 540-550 nm, thus confirming the synthesis of gold nanoparticles. Cord-Au-NPs have a crystalline structure, as evidenced by the diffraction peaks. The zeta potential value of -19.42 mV signifies the stability of Cord-Au-NPs. XRD study shows gold facets and EDX analysis revealed a strong peak of spherical nanoparticles in the gold region with a mean particle size of 7.18 nm and a polydispersity index of 0.096. The obtained peaks are closely associated with phenolic groups, lipids, and proteins, as examined by FTIR, suggesting that they function as the reducing agent. Cord-Au-NPs exhibited dose-dependent antioxidant, antidiabetic, and antibacterial activity. The method is eco-friendly, nontoxic, less time-consuming, and does not use synthetic materials, leading to higher capabilities in biomedical applications.
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