衍生化
试剂
化学
胺气处理
色谱法
显色的
柱色谱法
气相色谱法
高效液相色谱法
有机化学
作者
Rimadani Pratiwi,RIMADANI PRATIWI
出处
期刊:International Journal of Applied Pharmaceutics
[Innovare Academic Sciences]
日期:2023-01-07
卷期号:: 20-23
被引量:1
标识
DOI:10.22159/ijap.2023v15i1.46461
摘要
Derivatization is a modification process to produce a new compound that can be detected using the suitable detector in chromatography analysis. Derivatization reagent is needed to chemically modify a compound. One of a derivatization reagent that is widely used as a fluorogenic and chromogenic reagent in amine group’s analysis using chromatography is 4-Chloro-7-nitrobenzofurazan (NBD-Cl). NBD-Cl is considerable attraction because it plays a role in pre and post-column derivatizations fused in chromatography for increasing the selectivity and sensitivity. This review provides an overview of many papers that have been presented regarding the application of 4-Chloro-7-nitrobenzofurazan (NBD-Cl) in pre and post-column derivatization in amine group’s analysis and its chromatographic condition from the literature between 2000 to 2022.
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