Technetium-99m-Labeled Fibroblast Activation Protein-Targeted Nanobody Radiotracer: from Preclinical Development to Clinical Translation in Cancer Imaging

Tc]-Tc-AFN13 as a novel radiotracer with cross-reactivity to human and murine FAP. Its robust preclinical performance and promising clinical results highlight its potential for SPECT imaging in FAP-expressing cancers, paving the way for further clinical translation and theranostic applications.