神经炎症
疾病
神经科学
认知
阿尔茨海默病
淀粉样蛋白(真菌学)
认知功能衰退
痴呆
心理学
认知科学
医学
病理
出处
期刊:Science
[American Association for the Advancement of Science]
日期:2025-05-29
卷期号:388 (6750)
标识
DOI:10.1126/science.ady3217
摘要
With all the advances in both the science of aging and artificial intelligence (AI), we are in a propitious position to accurately and precisely determine who is at high risk of developing Alzheimer’s disease years before signs of even mild cognitive deficit. It takes at least 20 years for aggregates of misfolded β-amyloid and tau proteins to accumulate in the brain along with neuroinflammation that they incite. This provides a long window of opportunity to get ahead of the pathobiological process, both for prediction and prevention.
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